4-Chloroaniline → HCID 86660693, compound

HRID 1917002Notes

Reaction equation

HRID 1917002 reaction equation
[CH3:1][C:2]1([CH3:14])[CH:6]2[CH2:7][CH2:8][CH:3]1[CH:4]1[C:12](=[O:13])[O:11][C:9](=[O:10])[CH:5]12.[Cl:15][C:16]1[CH:22]=[CH:21][C:19]([NH2:20])=[CH:18][CH:17]=1>C(Cl)(Cl)Cl>[Cl:15][C:16]1[CH:22]=[CH:21][C:19]([NH:20][C:9]([C@@H:5]2[C@H:6]3[C:2]([CH3:1])([CH3:14])[C@H:3]([CH2:8][CH2:7]3)[C@@H:4]2[C:12]([OH:11])=[O:13])=[O:10])=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 78124-ChloroanilineHCID 58580345HCID 58580345, compound

Product 1

HCID 86660693HCID 86660693, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Following General Procedure A, Compound 3 (0.047 g, 0.24 mmol) and 4-chloroaniline (31 mg, 0.24 mmol) in chloroform (4 mL) was converted into the title compound, which was isolated as a white solid.

Sources & evidence

ORD record
ord-328d06f135ca4d069f288279813674aa
Source dataset
uspto-grants-2013_12
Patent number
US08618163B2

Reaction notes

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