HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Aladorian
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 16118509 | HCID 16118509 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | Aladorian | HCID 11161474 | 85.3% |
Reaction Steps
Compound 5 (740 mg) was dissolved in 30 mL of a mixture of THF, methanol and 1 M NaOH (1:1:1). The solution was stirred at r.t. for 6 hr and acidified with 1 N HCl. The organic solvent was removed and the resulting solid was collected and washed with water. The solid was dried under vacuum to give 600 mg solid with the yield of 85%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618282B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-51f33100bfab4e48b5c00de72f4b3123 |
| Source note | uspto-grants-2013_12 |