反应详情

2.4 g (11.6 mmol) of the triazine 2a and 7 mL (106 mmol) of acrylonitrile are placed in 24 mL of a solution of pyridine and water (1/1) under reflux for 3 h. After concentration, the reaction medium is extracted with AcOEt and then after drying on MgSO4, the organic phases are dry concentrated. After washing the obtained solid with ether, 2.8 g of intermediate 3a are obtained (yield=93%).

1. temperatureunder reflux for 3 h
2. concentrationAfter concentration
3. extractionthe reaction medium is extracted with AcOEt
4. customafter drying on MgSO4
5. customthe organic phases are dry
6. concentrationconcentrated
7. washAfter washing the obtained solid with ether, 2.8 g of intermediate 3a
8. customare obtained (yield=93%)