6-Bromo-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione → 1-Butanol

HRID 1917117Notes

Reaction equation

HRID 1917117 reaction equation
Br[C:2]1[C:3](=[O:11])[N:4]([CH3:10])[C:5](=[O:9])[N:6]([CH3:8])[N:7]=1.[F:12][C:13]1[CH:25]=[CH:24][C:16]([CH2:17][CH:18]2[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]2)=[C:15]([C:26]([F:29])([F:28])[F:27])[CH:14]=1>>[F:12][C:13]1[CH:25]=[CH:24][C:16]([CH2:17][CH:18]2[CH2:19][CH2:20][N:21]([C:2]3[C:3](=[O:11])[N:4]([CH3:10])[C:5](=[O:9])[N:6]([CH3:8])[N:7]=3)[CH2:22][CH2:23]2)=[C:15]([C:26]([F:29])([F:27])[F:28])[CH:14]=1.[CH2:3]([OH:11])[CH2:2][CH2:13][CH3:14]

Participants

4

Procedure

The compound 77 (oil) is prepared from the triazine 1b and from the intermediate 9b according to the synthesis method 1 in n-butanol (yield: 43%).

Sources & evidence

ORD record
ord-59a4368a0bdb43b3bbd980bc78aa38c4
Source dataset
uspto-grants-2013_12
Patent number
US08618287B2

Reaction notes

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