HCID 67490983, compound → HCID 67491022, compound

Participants

Reaction Steps

(1R,5S,6R)-1-tert-Butoxycarbonylamino-6-methyl-3-azabicyclo[3.2.0]heptane-3-carboxylic acid benzyl ester (180 mg, 0.59 mmol) was dissolved in a methanol (5 mL). A small amount of 10% palladium-carbon (50% wet) was added, and the mixture was stirred in a hydrogen atmosphere for one hour. After removing the catalyst by filtration, the filtrate was concentrated under reduced pressure to give 114 mg (85%) of the title compound as a colorless oil.

Provenance & Evidence