HCID 67491156, compound → HCID 67490924, compound

Participants

Reaction Steps

A 10% palladium-carbon catalyst (406 mg, 100 wt %) was added to a solution of (1S,6S)-1-tert-butoxycarbonylamino-8-[(1R)-1-phenylethyl]-8-azabicyclo[4.3.0]non-3-ene (406 mg, 1.18 mmol) in ethanol (11.8 mL) in a nitrogen atmosphere. After the atmosphere was replaced with hydrogen, the mixture was stirred in a hydrogen atmosphere at 40° C. to 50° C. for seven hours. After the atmosphere was replaced with nitrogen, the reaction solution was filtered through Celite and concentrated under reduced pressure to give the title compound quantitatively.

Provenance & Evidence