HCID 67490936, compound → HCID 67490912, compound

Participants

Reaction Steps

A 10% palladium-carbon catalyst (50% wet, 50 mg) was added to a solution of (1R*,6S*)-8-benzyl-6-(tert-butoxycarbonylamino)-2-oxa-8-azabicyclo[4.3.0]nonane (50 mg, 0.152 mmol) in methanol (10 mL), and the mixture was stirred in a hydrogen atmosphere at room temperature for 1.5 hours. The catalyst was removed by filtration, and then the solvent was evaporated under reduced pressure to give 45 mg of (1R*,6S*)-6-(tert-butoxycarbonylamino)-2-oxa-8-azabicyclo[4.3.0]nonane.

Provenance & Evidence