反应详情

10% Pd/C is added to compound 179 in ethanol:ethyl acetate:dichloromethane (2:1:1). The mixture is degassed and placed under H2 (1 atm) and stirred for 30 min The mixture is filtered through a 0.45 μm syringe filter and concentrated under reduced pressure to provide 180.

1. customThe mixture is degassed
2. filtrationis filtered through a 0.45 μm syringe
3. filtrationfilter
4. concentrationconcentrated under reduced pressure