HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Malic Acid → Sunitinib Malate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Malic Acid | HCID 222656 | — |
| Reactant | Sunitinib | HCID 5329102 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Sunitinib Malate | HCID 6456015 | — |
Reaction Steps
Sunitinib base (600 mg) was dissolved in pyridine (5 ml) at 100° C. and L-malic acid (230 mg) was added to the hot solution. Slight heating provided clear solution. Sunitinib malate was formed overnight at 20° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618309B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-d5e4d1852a6b449f8fd5222a74ae2d90 |
| Source note | uspto-grants-2013_12 |