HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Malic Acid → Sunitinib Malate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Malic Acid | HCID 222656 | — |
| Reactant | Sunitinib | HCID 5329102 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Sunitinib Malate | HCID 6456015 | — |
Reaction Steps
To Sunitinib base (300 mg), L-malic acid (101 mg), and AcOEt (10 ml) are added, the mixture is heated to 77 C for 10 min, after precipitation the obtained solid is filtered, dried on air.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618309B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-05ef6dc551c142de985b740b30c151e9 |
| Source note | uspto-grants-2013_12 |