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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1918301Generated: November 2, 2026

3-Methylbenzeneethanol → 1-[4-Chloro-3-(2-m-tolyl-ethoxy)-benzoylamino]-cycloheptanecarboxylic acid

https://huagongshe.com/reaction/1918301

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethylbenzeneethanolHCID 74648—
Reactant1-(4-Chloro-3-hydroxy-benzoylamino)-cycloheptanecarboxylic acid methyl esterHCID 67170384—
Product1-[4-Chloro-3-(2-m-tolyl-ethoxy)-benzoylamino]-cycloheptanecarboxylic acidHCID 67170064—

Reaction Steps

The compound of step 3 was etherified with 2-m-tolylethanol in analogy to step 1 of example 1, and the intermediate was hydrolyzed in analogy to step 4 of example 1 to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618304B2
Source datasetuspto-grants-2013_12
ORD IDord-fd847b3ab8994654a6fd8052ac915c6c
Source noteuspto-grants-2013_12