HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-hydroxy-4-methoxybenzoate → 3-{2-[3-(2-Hydroxy-ethyl)-phenyl]-ethoxy}-4-methoxy-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-hydroxy-4-methoxybenzoate | HCID 4056967 | — |
| Reactant | 2-[3-(2-Hydroxyethyl)phenyl]ethanol | HCID 10080741 | — |
| Product | 3-{2-[3-(2-Hydroxy-ethyl)-phenyl]-ethoxy}-4-methoxy-benzoic acid | HCID 67170710 | — |
Reaction Steps
2-[3-(2-Hydroxy-ethyl)-phenyl]-ethanol and 3-hydroxy-4-methoxybenzoic acid methyl ester were coupled in analogy to step 1 of example 1 and the methyl ester was hydrolyzed in analogy to step 2 of example 1 to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618304B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-b7e9aad6c4c041d6842cd032b4c2e178 |
| Source note | uspto-grants-2013_12 |