HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chlorophenethylic alcohol → 5-[2-(3-Chloro-phenyl)-ethoxy]-nicotinic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chlorophenethylic alcohol | HCID 78856 | — |
| Reactant | Ethyl 5-hydroxynicotinate | HCID 910016 | — |
| Product | 5-[2-(3-Chloro-phenyl)-ethoxy]-nicotinic Acid Ethyl Ester | HCID 67169864 | — |
Reaction Steps
5-Hydroxy-nicotinic acid ethyl ester and 2-(3-chlorophenyl)ethanol were etherified in a Mitsunobu reaction in analogy to step 3 of example 3 to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618304B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-c83b45f328be439f811ad62c3b1df508 |
| Source note | uspto-grants-2013_12 |