Water → HCID 67170971, compound

Participants

Reaction Steps

1.0 g of Methyl 4-fluoro-3-nitrobenzoate, 1.6 g of 3,3-Difluoro-cyclobutanol, and 3.3 g of Cs2CO3 were stirred in 10 ml of anhydrous DMF for 7 h at 60° C. The reaction mixture was then poured into 100 ml of water and extracted three times using 30 ml of EA each. The organic layer was dried using MgSO4 and volatiles were evaporated to yield 1.4 g of the title compound that was used without further purification.

Provenance & Evidence