HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Toluidine → 1-(3-Methylphenyl)-2-oxopyrrolidine-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Toluidine | HCID 7934 | — |
| Reactant | 6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione | HCID 79720 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(3-Methylphenyl)-2-oxopyrrolidine-3-carboxylic acid | HCID 4576309 | 84% |
Reaction Steps
This compound was prepared according to general method 1 starting from 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione (0.250 g, 1.47 mmol) and m-toluidine (0.470 mL; 4.41 mmol) in ethanol (3 mL). 2-oxo-1-m-tolylpyrrolidine-3-carboxylic acid 0.270 g (84%) was obtained as a pink film.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618138B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-05000a49e3c84230b9de2a6f8de9e51a |
| Source note | uspto-grants-2013_12 |