Ethyl bromoacetate → [6-(4',5'-Difluoro-2'-methoxy-biphenyl-4-yloxymethyl)-indol-1-yl]-acetic acid ethyl ester
Reaction equation
[CH2:1]([O:2][C:3](=[O:4])[CH2:5][CH2:6][n:7]1[cH:8][cH:9][c:10]2[cH:11][cH:12][c:13]([CH2:16][O:17][c:18]3[cH:19][cH:20][c:21](-[c:24]4[c:25]([O:32][CH3:33])[cH:26][c:27]([F:31])[c:28]([F:30])[cH:29]4)[cH:22][cH:23]3)[cH:14][c:15]12)[CH3:34].[CH2:62]([CH3:63])[O:64][C:65]([CH2:66][Br:67])=[O:68].[F:35][c:36]1[c:37]([F:38])[cH:39][c:40](-[c:41]2[cH:42][cH:43][c:44]([O:45][CH2:46][c:47]3[cH:48][c:49]4[c:50]([cH:51][cH:52][nH:53]4)[cH:54][cH:55]3)[cH:56][cH:57]2)[c:58]([O:59][CH3:60])[cH:61]1>>[CH2:6]([n:7]1[cH:8][cH:9][c:10]2[cH:11][cH:12][c:13]([CH2:16][O:17][c:18]3[cH:19][cH:20][c:21](-[c:24]4[c:25]([O:32][CH3:33])[cH:26][c:27]([F:31])[c:28]([F:30])[cH:29]4)[cH:22][cH:23]3)[cH:14][c:15]12)[C:65]([O:64][CH2:62][CH3:63])=[O:68]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-7562070be63e458ca8f2b19e7b6117ce
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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