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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1918949Generated: October 29, 2026

N-Methylisopropylamine → 6-Chloro-4-(5-((isopropyl(methyl)amino)methyl)pyridin-2-ylamino)-2-methylpyridazin-3(2H)-one

https://huagongshe.com/reaction/1918949

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylisopropylamineHCID 78485—
Reactant(6-(6-Chloro-2-methyl-3-oxo-2,3-dihydropyridazin-4-ylamino)pyridin-3-yl)methyl methanesulfonateHCID 58043865—
Product6-Chloro-4-(5-((isopropyl(methyl)amino)methyl)pyridin-2-ylamino)-2-methylpyridazin-3(2H)-oneHCID 58044131—

Reaction Steps

Following Example 186c, 180c and methylisopropylamine were reacted to give 180d.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618107B2
Source datasetuspto-grants-2013_12
ORD IDord-8edae77f08564e56b88808ee2a16ad0e
Source noteuspto-grants-2013_12