反应详情

温度

125 °C

In a 10-mL glass vessel equipped with a magnetic stirring bar were placed 197f (244 mg, 0.58 mmol), 197d (200 mg, 0.46 mmol), Pd(PPh3)4 (33 mg, 0.030 mmol) in 2 N Na2CO3 (1 mL) and DME (2 mL). The vessel was sealed with a septum and placed into the microwave cavity. After the reaction mixture was stirred at 125° C. for 7 min., it was purified by flash chromatography (dichloromethane:methanol, 85:15) to give 30% (90 mg) of 197g as a solid.

1. customIn a 10-mL glass vessel equipped with a magnetic stirring bar
2. customThe vessel was sealed with a septum
3. customit was purified by flash chromatography (dichloromethane:methanol, 85:15)