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HRID1919030

反应详情

EQUATION

反应方程式

HRID 1919030 的结构方程式

REACTANTS

反应物

2
结构：Cn1cc(Br)nc(Nc2ccc3c(c2)CNC3)c1=O
HCID58043707

未命名化合物

结构：CC(C)N1CCN(c2ccc(Nc3cc(Br)cn(C)c3=O)nc2)CC1
HCID58043758

2(1H)-Pyridinone, 5-bromo-1-methyl-3-[[5-[4-(1-methylethyl)-1-piperazinyl]-2-pyridinyl]amino]-

C18H24BrN5O

PRODUCTS

生成物

1
结构：CN1Cc2ccc(Nc3nc(Br)cn(C)c3=O)cc2C1
HCID58043770

未命名化合物

PROCEDURE

实验过程

Following the procedures as described for 220a and starting with 336 mg of 5-bromo-3-(isoindolin-5-ylamino)-1-methylpyrazin-2(1H)-one, compound 231f was obtained as a yellow solid (237 mg, 75%). MS: [M+H]+ 337. 1H NMR (500 MHz, CDCl3) δ 8.31 (s, 1H), 7.67 (s, 1H), 7.52 (t, J=7.0, 1H), 7.18 (d, J=8.0, 1H), 6.74 (s, 1H), 3.94 (s, 2H), 3.89 (s, 2H), 3.52 (s, 3H), 2.60 (s, 3H).