(6S)-1,4-Diazabicyclo(4.3.0)nonane → 5-Chloro-2-[(S)-1-(hexahydro-pyrrolo[1,2-a]pyrazin-2-yl)methyl]-7-morpholin-4-ylthiazolo[4,5-d]pyrimidine

Participants

Reaction Steps

Prepared according to the method used in the preparation of 5-(5-chloro-7-morpholin-4-ylthiazolo[4,5-d]pyrimidin-2-ylmethyl)-hexahydro-pyrrolo[3,4-c]pyrrole-2-carboxylic acid tert-butyl ester using (S)-octahydro-pyrrolo[1,2-a]pyrazine in place of hexahydro-pyrrolo[3,4-c]pyrrole-2-carboxylic acid tert-butyl ester. The title compound was obtained as an orange solid (131 mg, 46%).

Provenance & Evidence