HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethylpiperidin-4-amine → [1-(5-Chloro-7-morpholin-4-ylthiazolo[5,4-d]pyrimidin-2-ylmethyl)piperidin-4-yl]dimethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethylpiperidin-4-amine | HCID 417391 | — |
| Reactant | 2-(4-Azetidin-1-ylpiperidin-1-ylmethyl)-5-chloro-7-morpholin-4-ylthiazolo[5,4-d]pyrimidine | HCID 58234933 | — |
| Product | [1-(5-Chloro-7-morpholin-4-ylthiazolo[5,4-d]pyrimidin-2-ylmethyl)piperidin-4-yl]dimethylamine | HCID 58234944 | — |
Reaction Steps
Prepared according to the method used in the preparation of 2-(4-azetidin-1-ylpiperidin-1-ylmethyl)-5-chloro-7-morpholin-4-ylthiazolo[5,4-d]pyrimidine using dimethylpiperidin-4-ylamine in place of 4-azetidin-1-ylpiperidine. The title compound was obtained as a pale yellow solid (101 mg, 72%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08168633B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-2cfb0366fdad491f96e0706106b3efcd |
| Source note | uspto-grants-2012_05 |