Sodium Azide → HCID 86628906, compound

Participants

Reaction Steps

Following the general procedure for the preparation of azides of Description 16, (ethoxycarbonyloxy)ethyl (2R)-4-[(3-chloropropyl)sulfonyloxy]-3,3-dimethyl-2-(2-methylpropanoyloxy)butanoate (36c) (0.23 g, 0.49 mmol) dissolved in 3 mL of anhydrous dimethyl sulfoxide (DMSO) was reacted with 64 mg (0.98 mmol) of sodium azide (NaN3). After work-up, the crude material (36d) was obtained and used in the next step without further purification. MS (ESI) m/z 504.01 (M+Na)+.

Provenance & Evidence