HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59322472, compound → HCID 67497844, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59322472 | HCID 59322472 | — |
| Reactant | HCID 86641594 | HCID 86641594 | — |
| Product | HCID 67497844 | HCID 67497844 | — |
Reaction Steps
Compound (11) is reacted with compound (18) in a suitable solvent to give 3-(4-biphenylyl)-2-[N-(5-dibenzylaminopentyl)-N-methylamino]-4-methoxycarbonylmethyl-3,4-dihydroquinazoline (19). Then, this compound (19) is hydrogenated in the presence of Pd(C) and formalin solution to give 2-[N-(5-N′,N′-dimethylaminopentyl)-N-methylamino]-3-(4-biphenylyl)-4-methoxycarbonylmethyl-3,4-dihydroquinazoline (20).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08168646B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-57cd8d7efddd464e9c1fd2a2027efae2 |
| Source note | uspto-grants-2012_05 |