1-[4-(2-n-Butyloxyethoxymethyl)phenoxy]-2,3-epoxypropane → 6-[4-[2-[3-(4-(2-n-Butyloxyethoxy-methyl)phenoxy)-2-hydroxypropylamino]ethoxy]-3-chloro-phenyl]-4,5-dihydro-3-(2H)-pyridazinone

HRID 191964Notes

Reaction equation

HRID 191964 reaction equation
[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][CH2:6][CH2:7][O:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([O:14][CH2:15][CH:16]2[CH2:17][O:18]2)[cH:19][cH:20]1.[NH2:21][CH2:22][CH2:23][O:24][c:25]1[c:26]([Cl:38])[cH:27][c:28]([C:31]2=[N:36][NH:35][C:34](=[O:37])[CH2:33][CH2:32]2)[cH:29][cH:30]1>>[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][CH2:6][CH2:7][O:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([O:14][CH2:15][CH:16]([CH2:17][NH:21][CH2:22][CH2:23][O:24][c:25]2[c:26]([Cl:38])[cH:27][c:28]([C:31]3=[N:36][NH:35][C:34](=[O:37])[CH2:33][CH2:32]3)[cH:29][cH:30]2)[OH:18])[cH:19][cH:20]1

Participants

3

Reactant 2

HCID 151078111-[4-(2-n-Butyloxyethoxymethyl)phenoxy]-2,3-epoxypropaneHCID 151078226-[4-(2-aminoethoxy)-3-chloro-phenyl]-4,5-dihydro-3(2H)-pyridazinone

Product 1

HCID 151078786-[4-[2-[3-(4-(2-n-Butyloxyethoxy-methyl)phenoxy)-2-hydroxypropylamino]ethoxy]-3-chloro-phenyl]-4,5-dihydro-3-(2H)-pyridazinone

Sources & evidence

ORD record
ord-6aeb40f7b2404d03ba5c065bbfb024ca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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