HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Isocyanato-2-methoxybenzonitrile → 4-[4-(4-Hydroxyphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-2-methoxybenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Isocyanato-2-methoxybenzonitrile | HCID 14847856 | — |
| Reactant | Methyl 2-amino-2-(4-hydroxyphenyl)propionate | HCID 59235258 | — |
| Product | 4-[4-(4-Hydroxyphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-2-methoxybenzonitrile | HCID 59235256 | — |
Reaction Steps
The procedure of Example C is used, with 4-cyano-3-methoxyphenyl isocyanate starting from 2.2 g of methyl 2-amino-2-(4-hydroxyphenyl)propionate. After chromatography over silica and evaporation of the solvents 3.6 g of product, a yellowish solid, is obtained (Yd=92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08168667B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-a9da6cc2820e46218e673e8544f32df3 |
| Source note | uspto-grants-2012_05 |