Methyl 2-bromo-2-(3-methoxyphenyl)acetate → HCID 59235275, compound

HRID 1919784Notes

Reaction equation

HRID 1919784 reaction equation
Br[CH:2]([C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([O:13][CH3:14])[CH:8]=1)[C:3]([O:5][CH3:6])=[O:4].OC1C=CC([C:22]([NH:28]C)(C)C(OC)=O)=CC=1>>[CH3:14][O:13][C:9]1[CH:8]=[C:7]([CH:2]([NH:28][CH3:22])[C:3]([O:5][CH3:6])=[O:4])[CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 289522Methyl 2-bromo-2-(3-methoxyphenyl)acetateHCID 59235252Methyl 2-(4-hydroxyphenyl)-2-methylaminopropionate

Product 1

HCID 59235275HCID 59235275, compound

Procedure

Starting from 14.5 g of methyl 2-bromo-2-(3-methoxyphenyl)acetate, 7.5 g of product are prepared by the process used above when preparing methyl 2-(4-hydroxyphenyl)-2-methylaminopropionate (yellow oil; Yd=65%).

Workup

  1. customare prepared by the process

Sources & evidence

ORD record
ord-47c8a33e4e0d4a23803392eb5352831a
Source dataset
uspto-grants-2012_05
Patent number
US08168667B2

Reaction notes

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