HCID 44137409, compound → HCID 67160136, compound

HRID 1919858Notes

Reaction equation

HRID 1919858 reaction equation
C([O:3][C:4](=[O:33])[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][C:11]([F:15])=[CH:12][CH:13]=2)[C:8]([CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([S:23]([N:26]3[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]3)(=[O:25])=[O:24])[CH:18]=2)=[C:7]1[CH3:32])C.C1(S(C2C=CC=CC=2CC2C3C(=CC=C(F)C=3)N(CC(O)=O)C=2C)(=O)=O)CCCCC1>>[F:15][C:11]1[CH:10]=[C:9]2[C:14](=[CH:13][CH:12]=1)[N:6]([CH2:5][C:4]([OH:33])=[O:3])[C:7]([CH3:32])=[C:8]2[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([S:23]([N:26]2[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]2)(=[O:24])=[O:25])[CH:18]=1

Participants

3

Reactant 2

HCID 44137409HCID 44137409, compoundHCID 67490752HCID 67490752, compound

Product 1

HCID 67160136HCID 67160136, compound

Procedure

2-(5-fluoro-2-methyl-3-(3-(piperidin-1-ylsulfonyl)benzyl)-1H-indol-1-yl)acetic acid ethyl ester was used as a starting material, otherwise this compound was prepared in a similar manner to Compound 1, using Procedure L.

Sources & evidence

ORD record
ord-623b14bfadab41cc9e2e1f0dd9e40847
Source dataset
uspto-grants-2012_05
Patent number
US08168673B2

Reaction notes

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