Sulfuric Acid → HCID 86633023, compound

Participants

Reaction Steps

To a solution of 1-(cyclohexylsulfonyl)-4-(dimethoxymethyl)benzene (117 mg, 0.392 mmol) in THF (4 mL) was added an aqueous solution of sulfuric acid (2% v/v, 2 mL) and the resulting mixture stirred for 18 hours at room temperature. Excess solid potassium carbonate was then added, and the mixture diluted with water. Finally, the aqueous solution was extracted with ethyl acetate (×3), and the combined organic phases dried over anhydrous magnesium sulfate, filtered and evaporated in vacuo to give 4-(cyclohexylsulfonyl)benzaldehyde (1100 mg, quantitative yield) as a colourless oil.

Provenance & Evidence