Acetyl chloride → HCID 44159408, compound

HRID 1919947Notes

Reaction equation

HRID 1919947 reaction equation
C[O:2][C:3](=[O:30])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=2[CH2:23][NH:24][CH2:25][C:26]([F:29])([F:28])[F:27])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1.[C:31](Cl)(=[O:33])[CH3:32]>>[C:31]([N:24]([CH2:23][C:14]1[CH:15]=[C:16]([C:19]([F:20])([F:21])[F:22])[CH:17]=[CH:18][C:13]=1[C:7]1[C:8]([O:11][CH3:12])=[CH:9][CH:10]=[C:5]([CH2:4][C:3]([OH:2])=[O:30])[CH:6]=1)[CH2:25][C:26]([F:29])([F:27])[F:28])(=[O:33])[CH3:32]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 86633168HCID 86633168, compound

Product 1

HCID 44159408HCID 44159408, compound

Procedure

Prepared according to the procedure described in Example 1, Step 6 and Step 7, using the following starting materials: {6-methoxy-2′-[(2,2,2-trifluoro-ethylamino)-methyl]-4′-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester and acetyl chloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-60595e8a3cdd400ebcefcd8e305048ca
Source dataset
uspto-grants-2012_05
Patent number
US08168678B2

Reaction notes

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