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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1919950Generated: October 31, 2026

Acetyl chloride → {2'-[(Acetyl-ethyl-amino)-methyl]-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester

https://huagongshe.com/reaction/1919950

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
Reactant(2'-Ethylaminomethyl-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl esterHCID 66603778—
Product{2'-[(Acetyl-ethyl-amino)-methyl]-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl esterHCID 66604034—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-ethylaminomethyl-6-fluoro-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester and acetyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08168678B2
Source datasetuspto-grants-2012_05
ORD IDord-c608418ef3c2451d89c60c37f96e41f2
Source noteuspto-grants-2012_05