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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1919955Generated: October 31, 2026

Methylamine → (6-Fluoro-2'-methylaminomethyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

https://huagongshe.com/reaction/1919955

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant(6-Fluoro-2'-formyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl esterHCID 86633169—
Product(6-Fluoro-2'-methylaminomethyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl esterHCID 66604100—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 5, using the following starting materials: (6-fluoro-2′-formyl-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester and methylamine (2M in THF).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08168678B2
Source datasetuspto-grants-2012_05
ORD IDord-12ae48cae6dc4933856b22dcc51ceabe
Source noteuspto-grants-2012_05