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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1919956Generated: October 31, 2026

Benzyl chloroformate → {2'-[(Benzyloxycarbonyl-methyl-amino)-methyl]-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester

https://huagongshe.com/reaction/1919956

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl chloroformateHCID 10387—
Reactant(6-Fluoro-2'-methylaminomethyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl esterHCID 66604100—
Product{2'-[(Benzyloxycarbonyl-methyl-amino)-methyl]-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl esterHCID 66605065—

Reaction Steps

Prepared according to the procedure described in Example 7, Step 1, using the following starting materials: (6-fluoro-2′-methylaminomethyl-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester and benzyl chloroformate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08168678B2
Source datasetuspto-grants-2012_05
ORD IDord-9d27fbf8aab84a7db1f0808265f11137
Source noteuspto-grants-2012_05