Ethylamine → 2-Bromo-N-ethyl-5-(trifluoromethyl)benzenemethanamine

HRID 1919966Notes

Reaction equation

[Br:1][C:2]1[CH:9]=[CH:8][C:7]([C:10]([F:13])([F:12])[F:11])=[CH:6][C:3]=1[CH:4]=O.[CH2:14]([NH2:16])[CH3:15]>>[Br:1][C:2]1[CH:9]=[CH:8][C:7]([C:10]([F:13])([F:12])[F:11])=[CH:6][C:3]=1[CH2:4][NH:16][CH2:14][CH3:15]

Participants

Reactant 2

HCID 6341Ethylamine

HCID 70180472-Bromo-5-(trifluoromethyl)benzaldehyde

Product 1

HCID 666039992-Bromo-N-ethyl-5-(trifluoromethyl)benzenemethanamine

Procedure

Prepared according to the procedure described in Example 11, Step 4, using the following starting materials: 2-bromo-5-(trifluoromethyl)benzaldehyde and ethylamine (2M in THF).

Workup

customPrepared

Sources & evidence

ORD record: ord-76f894abc7814714b65b6c377c1da531
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08168678B2

Reaction notes

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