2-Bromo-5-(trifluoromethyl)benzaldehyde → HCID 86633174, compound

HRID 1919986Notes

Reaction equation

HRID 1919986 reaction equation
[CH3:1][O:2][C:3](=[O:20])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7](B2OC(C)(C)C(C)(C)O2)[CH:6]=1.Br[C:22]1[CH:29]=[CH:28][C:27]([C:30]([F:33])([F:32])[F:31])=[CH:26][C:23]=1[CH:24]=[O:25]>>[CH3:1][O:2][C:3](=[O:20])[CH2:4][C:5]1[CH:6]=[C:7]([C:22]2[CH:29]=[CH:28][C:27]([C:30]([F:33])([F:32])[F:31])=[CH:26][C:23]=2[CH:24]=[O:25])[CH:8]=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 70180472-Bromo-5-(trifluoromethyl)benzaldehydeHCID 110977913-(2-Methoxy-2-oxoethyl)phenylboronic acid, pinacol ester

Product 1

HCID 86633174HCID 86633174, compound

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: [3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid methyl ester and 2-bromo-5-(trifluoromethyl)benzaldehyde.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-79b81a8d209c491cbc83f27dcc9da5c7
Source dataset
uspto-grants-2012_05
Patent number
US08168678B2

Reaction notes

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