Ethylamine → HCID 66604171, compound

HRID 1920002Notes

Reaction equation

HRID 1920002 reaction equation
[CH2:1]([O:3][C:4](=[O:32])[CH2:5][C:6]1[CH:7]=[C:8]([C:20]2[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:28])[F:27])=[CH:22][C:21]=2[CH:30]=O)[C:9]([O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:10][CH:11]=1)[CH3:2].[CH2:33]([NH2:35])[CH3:34]>>[CH2:1]([O:3][C:4](=[O:32])[CH2:5][C:6]1[CH:7]=[C:8]([C:20]2[CH:25]=[CH:24][C:23]([C:26]([F:27])([F:28])[F:29])=[CH:22][C:21]=2[CH2:30][NH:35][CH2:33][CH3:34])[C:9]([O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:10][CH:11]=1)[CH3:2]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 86633175HCID 86633175, compound

Product 1

HCID 66604171HCID 66604171, compound

Procedure

Prepared according to the procedure described in Example 1, Step 5, using the following starting materials: (6-benzyloxy-2′-formyl-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester and ethylamine (2M in THF).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d118cabebc3c43098fe208c7297fad93
Source dataset
uspto-grants-2012_05
Patent number
US08168678B2

Reaction notes

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