HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1920092Generated: November 1, 2026
Chloral → 4-bromo-N-(2,2,2-trichloro-1-hydroxyethyl)furan-2-carboxamide
https://huagongshe.com/reaction/1920092
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chloral | HCID 6407 | — |
| Reactant | 4-Bromofuran-2-carboxamide | HCID 57589975 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 4-bromo-N-(2,2,2-trichloro-1-hydroxyethyl)furan-2-carboxamide | HCID 58149535 | — |
Reaction Steps
A mixture of 4-bromofuran-2-carboxamide 124 (0.85 g, 4.47 mmol) and chloral (0.78 mL) in xylene was heated at 95° C. for 1.5 hours. The mixture was concentrated to give 4-bromo-N-(2,2,2-trichloro-1-hydroxyethyl)furan-2-carboxamide 125 as a tan solid that was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08168795B2 |
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| Source dataset | uspto-grants-2012_05 |
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| ORD ID | ord-85fa58047fe6478994aa4971d1c9303b |
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| Source note | uspto-grants-2012_05 |
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