Pyridine → N-[3-(ethoxymethyl)isoquinolin-5-yl]-1,5,10,10a-tetrahydro-[1,3]thiazolo[3,4-b]isoquinolin-3-imine
Reaction equation
[CH3:2][S:3][C:4]1=[N+:8]2[CH:7]([CH2:6][S:5]1)[CH2:16][c:15]1[c:10]([cH:11][cH:12][cH:13][cH:14]1)[CH2:9]2.[I-:1].[NH2:17][c:18]1[c:19]2[cH:20][c:21]([CH2:28][O:29][CH2:30][CH3:31])[n:22][cH:23][c:24]2[cH:25][cH:26][cH:27]1.[cH:32]1[cH:33][cH:34][n:35][cH:36][cH:37]1>>[C:4]1(=[N:17][c:18]2[c:19]3[cH:20][c:21]([CH2:28][O:29][CH2:30][CH3:31])[n:22][cH:23][c:24]3[cH:25][cH:26][cH:27]2)[S:5][CH2:6][CH:7]2[N:8]1[CH2:9][c:10]1[cH:11][cH:12][cH:13][cH:14][c:15]1[CH2:16]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-392438929db941d29fb8876ae98debd7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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