Acetonitrile → HCID 23565296, compound

Participants

Reaction Steps

4-(tert-butoxycarbonylamino)piperidine (150 mg) was added to acetonitrile (5 mL), and triethylamine (0.21 mL) and ethyloxalyl chloride (0.11 mL) were added dropwise at 0° C. The reaction solution was stirred for 30 minutes and an aqueous saturated sodium hydrogen carbonate solution was added, followed by extraction with ethyl acetate. The organic layer was washed in turn with water and saturated brine, dried over anhydrous magnesium sulfate and then concentrated under reduced pressure to obtain the title compound (235 mg) having the following physical properties.

Provenance & Evidence