HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 68919438, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Chloro-3-nitropyridine | HCID 2735781 | — |
| Reactant | HCID 59455680 | HCID 59455680 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 68919438 | HCID 68919438 | 98% |
Reaction Steps
Method 1 was followed using 1 eq each of 4-chloro-3-nitropyridine, tert-butyl (3S,4S)-4-(tert-butyldimethylsilyloxy)piperidin-3-ylcarbamate and triethylamine in DMF yielding tert-butyl(3S,4S)-4-(tert-butyldimethylsilyloxy)-1-(3-nitropyridin-4-yl)piperidin-3-ylcarbamate, (98%). LCMS (m/z): 453.3 (MH+); LC Rt=4.01 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08168794B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-13fd26cecf05492f8c518ae91fd668d6 |
| Source note | uspto-grants-2012_05 |