HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-3-((trifluoromethyl)sulfonyl)benzenesulfonamide → 4-[[(1R)-3-(4-Morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-3-((trifluoromethyl)sulfonyl)benzenesulfonamide | HCID 25058452 | — |
| Reactant | (R)-4-Morpholino-1-(phenylthio)-2-butylamine | HCID 25058453 | — |
| Product | 4-[[(1R)-3-(4-Morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]benzenesulfonamide | HCID 25058454 | — |
Reaction Steps
reacting 4-fluoro-3-((trifluoromethyl)sulfonyl)benzenesulfonamide, (1R)-3-morpholin-4-yl-1-((phenylthio)methyl)propylamine and a sixth base to provide 4-(((1R)-3-morpholin-4-yl-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide and isolating or not isolating the 4-(((1R)-3-morpholin-4-yl-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide; and
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08168784B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-b044f7a788a6475d9d3235668cb4dfc2 |
| Source note | uspto-grants-2012_05 |