Ethanol → HCID 25143768, compound

Participants

Reaction Conditions

Reaction Steps

Added 3.46 grams of compound N,N-diethyl-5-methylhex-2-enamide (formula-4-a) to a mixture of 0.863 gram of potassium cyanide and 3.5 grams of ethanol. Stirred the reaction mixture for 18 hours at 25-40° C. Added 4.45 ml of hexane to the reaction mixture. Added 0.875 gram of glacial acetic acid to the reaction mixture at 35° C. Quenched the reaction mixture with water. Separated the organic and aqueous phases. Extracted the aqueous phase with hexane. Washed the organic layer with water. Distilled the organic phase under reduced pressure to get the title compound as a residue

Provenance & Evidence