Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl 4-[ethyl(3-methylphenyl)amino]butanoate | HCID 66966695 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 23111119 | HCID 23111119 | 109.5% |
Reaction Steps
4N Solution (100 ml) of hydrogen chloride in dioxane and water (20 ml) was added to the compound (14.1 g) obtained in Step 1, and the mixture was stirred at 95° C. for 12 hours. The solvent was evaporated to give the title compound (13.7 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08168827B2 |
|---|
| Source dataset | uspto-grants-2012_05 |
|---|
| ORD ID | ord-1dd2e6955179498ebe802ccb20f38160 |
|---|
| Source note | uspto-grants-2012_05 |
|---|
