Hydrogen Bromide → HCID 67495975, compound

Participants

Reaction Steps

To a stirred solution of (R)-1-(3-tert-Butoxycarbonyl-propyl)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-azonia-bicyclo[2.2.2]octane bromide [Example 163] (0.2 g, 0.41 mmol) in methylene chloride (1.5 ml) under an argon atmosphere at room temperature is added hydrobromic acid (33% in acetic acid, 0.36 ml). After stirring at room temperature for 30 minutes, concentration is followed by dissolution in water/acetonitrile and stirring for a further 30 minutes. Concentration then gives the title product.

Provenance & Evidence