HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Chloro-3-oxopropyl acrylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Carboxyethyl acrylate | HCID 90558 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Chloro-3-oxopropyl acrylate | HCID 57428991 | — |
Reaction Steps
2-Carboxyethyl acrylate (1 eq.) is dissolved in CH2Cl2 and the solution is cooled in an ice bath. Thionyl chloride (1 eq.) is added dropwise and the mixture is allowed to warm to room temperature and stir for 4 hours. The solvent is removed under reduced pressure and the desired product is isolated by vacuum distillation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08172873B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-3f3abedbb19f4df180d7ce0333dcec44 |
| Source note | uspto-grants-2012_05 |