HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Methyl-L-Tyrosine → (S)-2-(Biphenyl-3-ylamino)-3-(4-methoxy-phenyl)-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Methyl-L-Tyrosine | HCID 2723935 | — |
| Reactant | (S)-2-(Biphenyl-3-ylamino)-3-(3,4,5-trimethoxy-phenyl)-propionic acid | HCID 11384247 | — |
| Product | (S)-2-(Biphenyl-3-ylamino)-3-(4-methoxy-phenyl)-propionic acid | HCID 67492714 | — |
Reaction Steps
The title compound is prepared as described for (S)-2-(Biphenyl-3-ylamino)-3-(3,4,5-trimethoxy-phenyl)-propionic acid (example 1) but using O-methyl-L-tyrosine (Bachem). Purification by MPLC (CH3CN/H2O/TFA) afforded the title compound; ES-MS: 348.3 [M+H]+; HPLC: single peak at tR=9.52 min (System 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173128B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-90d0e67d02df4817b106391e8aed6703 |
| Source note | uspto-grants-2012_05 |