HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dimethoxyphenylalanine, L- → (S)-2-(Biphenyl-3-ylamino)-3-(3,4-dimethoxyphenyl)-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dimethoxyphenylalanine, L- | HCID 10632946 | — |
| Reactant | (S)-2-(Biphenyl-3-ylamino)-3-(3,4,5-trimethoxy-phenyl)-propionic acid | HCID 11384247 | — |
| Product | (S)-2-(Biphenyl-3-ylamino)-3-(3,4-dimethoxyphenyl)-propionic acid | HCID 67492614 | — |
Reaction Steps
The title compound is prepared as described for (S)-2-(Biphenyl-3-ylamino)-3-(3,4,5-trimethoxy-phenyl)-propionic acid (example 1) but using 3-(3,4-dimethoxyphenyl)-L-alanine (Aldrich). Purification by MPLC (CH3CN/H2O/TFA) afforded the title compound; ES-MS: 378.2 [M+H]+; HPLC: single peak at tR=9.10 min (System 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173128B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-c953ec6f317c4715b3dcc32bc45dd142 |
| Source note | uspto-grants-2012_05 |