HCID 59526799, compound → HCID 59526816, compound

Participants

Reaction Steps

The title compound is prepared from ethyl 1-cyclopropyl-7-fluoro-2-mercapto-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate using the method described above for the preparation of 9-cyclopropyl-6,7-difluoro-3-hydroxyl-8-methoxy-4-oxo-4,9-dihydrothieno[2,3-b]quinoline-2-carbonitrile. 1H NMR: δ1.03 (br, 2H), 1.27 (m, 2H), 3.90 (m, 1H), 3.94 (s, 3H), 7.45 (m, 1H), 8.02 (m, 1H). 19F NMR: δ−121.70 (s). LCMS: m/z calcd for C16H11FN2O3S ([M]+) 330. found ([M+H]+) 331.

Provenance & Evidence