Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Aspirin | HCID 2244 | — |
| Reactant | Rosuvastatin Calcium | HCID 5282455 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 62705023 | HCID 62705023 | — |
Reaction Steps
The highly non-crystalline glass state of the combination of rosuvastatin calcium and aspirin was produced by applying a repeated sequence of short wavelength followed by long wavelength laser light modulated and structured by a Strachan Device. A 60 mg sample of rosuvastatin calcium and a 60 mg sample of crystalline aspirin were dissolved in 1200 mg of absolute ethanol by stirring at 9000 rpm with a magnetic stirrer, while heating to 140° C. for 10 minutes in a stoppered Erlenmeyer flask. The solution was filtered, and then divided equally into 6 polystyrene Petri dishes for producing treated and untreated control samples and each sample was covered with a polystyrene lid. The samples were allowed to cool to room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08173632B2 |
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| Source dataset | uspto-grants-2012_05 |
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| ORD ID | ord-da1b4bd000144fddae18885eaee024b1 |
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| Source note | uspto-grants-2012_05 |
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