Morpholine → HCID 59198413, compound

HRID 1920826Notes

Reaction equation

HRID 1920826 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[N:10][C:11]([NH2:14])=[N:12][CH:13]=2)[CH:5]=[C:4](Cl)[N:3]=1.[NH:16]1[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1>C(#N)C>[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[N:10][C:11]([NH2:14])=[N:12][CH:13]=2)[CH:5]=[C:4]([N:16]2[CH2:21][CH2:20][O:19][CH2:18][CH2:17]2)[N:3]=1

Participants

4

Reactant 2

HCID 8083MorpholineHCID 59198389HCID 59198389, compound

Product 1

HCID 59198413HCID 59198413, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

According to Method 6, the reaction of 2,6-dichloro-4,5′-bipyrimidin-2′-amine with morpholine in acetonitrile gave 2-chloro-6-morpholino-4,5′-bipyrimidin-2′-amine. LCMS (m/z): 293.0 (MH+); Rt 1.92 min.

Sources & evidence

ORD record
ord-338d59579fbc4bbea055cfca53d3ea10
Source dataset
uspto-grants-2012_05
Patent number
US08173647B2

Reaction notes

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