Morpholine → HCID 59198374, compound

HRID 1920828Notes

Reaction equation

HRID 1920828 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[N:10][C:11]([NH:14][CH3:15])=[N:12][CH:13]=2)[CH:5]=[C:4](Cl)[N:3]=1.[NH:17]1[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>C(#N)C>[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[N:10][C:11]([NH:14][CH3:15])=[N:12][CH:13]=2)[CH:5]=[C:4]([N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)[N:3]=1

Participants

4

Reactant 2

HCID 8083MorpholineHCID 59198370HCID 59198370, compound

Product 1

HCID 59198374HCID 59198374, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

According to Method 6, the reaction of 2,6-dichloro-N-methyl-4,5′-bipyrimidin-2′-amine with morpholine in acetonitrile gave 2-chloro-N-methyl-6-morpholino-4,5′-bipyrimidin-2′-amine.

Sources & evidence

ORD record
ord-7807d692c3dc485c884c032d5530ebc8
Source dataset
uspto-grants-2012_05
Patent number
US08173647B2

Reaction notes

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